Anatomic lesions
CLINICAL NUTRITION
Lesson 2: Protein calorie malnutrition
Anatomic lesion
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Following functional changes, anatomic lesions become manifest. At first, they are “subgross”, that is, microscopic in nature. Hence, early investigation of tissues readily available for examination with the bio-microscope such as the conjunctiva, the cornea, the tongue is entirely reasonable. Since these tissues are known eventually to develop gross lesions as a result of tissue depletion.
- The conjuctiva develop Bitot’s spots in advanced vitamin ‘A’ deficiency.
- The cornea may develop increased and nutritional and abnormal vascularity in riboflavin deficiency.
- The tongue shows glossitis in several vitamin ‘B’ deficiency diseases.
Progression of subgross lesions leads to gross manifestation becoming evident. These are described collectively as the clinical signs.
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Last modified: Wednesday, 2 November 2011, 9:38 AM