Agents responsible for liver damage

Normal and Therapeutic Nutrition 3(2+1)
Lesson 24:Liver diseases-Jaundice-causes, symptoms, dietary management

Agents responsible for liver damage

  1. Dietary deficiencies
    • Fatty changes in kwashiorkor due to low protein, severely low ? lipoprotein
    • High intake of fats or carbohydrates
  2. Infective agents
    • Virus infections causes hepatitis A,B,C,D,E and G
    • Type- E is dangerous during pregnancy.
    • Hepatitis A and E virus contaminates through faecal-oral route leading jaundice and liver enlargement
    • Hepatitis B, C, D and G virus cause homologous serum jaundice with low blood or blood products of carrier, unsterilized needles
    • Yellow fever, typhoid, Weil's disease (spirochete) and amoebiasis
  3. Toxic agents
    • Alcohol intake enhancing fatty acid synthesis
    • Decreasing fatty acid oxidation
    • Specific stimulation to triglycerides
  4. Drugs and chemicals: paracetamol and oestrogen
    Excess stores of iron, copper, galactose, glycogen leading to Cirrhosis
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Last modified: Tuesday, 25 October 2011, 5:02 AM