Aujezkey's disease
Synonym: Pseudorabies, infectious bulbar paralysis, mad itch
Definition
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This is a disease affecting many species of animals (pigs, cattle, dogs, cats, sheep and rats etc.) caused by pantropic virus belonging to the group of herpes viruses
Etiology
Incidence
Susceptibilty
Transmission
Pathogenesis
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Virus affects all embryonic layers
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Via Peripheral nerves invade into the sp. cord- local reaction on the muscle and fascia- necrosis
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Spinal cord – Ganglia showed neuronal degeneration and proliferation of glial cells
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Pruritus (itching)
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Non purulent encephalomyelitis.
Clinical signs
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Cattle
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Biting and kicking with continuou maniacal behavior.
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Paralysis – Pyrexia and death within 6 to 48 hrs.
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Some cases - Sudden death without any symptoms.
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Young pigs are usuallly affected
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Swine
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Pigs – paralysis, incoordination, convulsion, tremors, vomition.
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Pruritus is not seen in pigs
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Death occurs within 12 hours in young pigs
Gross lesions
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Inflammation, pulmonary oedema, pneumonia, laryngitis, gastroenteritis, myocarditis,
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Necrosis of spleen and liver
Microscoic lesions
Diagnosis
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Last modified: Monday, 19 March 2012, 5:19 AM