Transmissible gastroenteritis of swine
TRANSMISSIBLE GASTROENTERITIS OF SWINE
|
-
First described in 1946. It is a highly contagious viral disease of young pigs. Clinically characterized by vomition, diarrhoea, dehydration and high mortality rate up to 100% in piglet under 2 weeks of age
Etiology
Incidence
Susceptibility
Transmission
Pathogenesis
- Virusinfects the upper respiratory tract and intestine
- Virus infects mature columnar epithelial cells of villibut not the undifferentiated cells in crypts
- Replication occurs in 4 – 5 hours
- With sloughing of infected cells and release of virus
- After several replications there is marked reduction in villous size with villous atrophy in small intestine
- Undifferentiated cells from crypts proliferate
- Mainly jejunum is affected
Clinical signs
-
Piglets < 10 dats of age
-
Diarrhoea
-
Vomition
-
Excessive thirst
-
Weight loss
-
Dehydration
-
Death 2 – 5 days
-
Older piglets & adults
-
Profuse diarrhoea
-
Vomition
-
Failure to gain weight
Morbidity and Mortality
Gross lesions
Microscopical lesions
Diagnosis
-
Clinical signs
-
Histopathology of small intestine
-
ELISA, IFT, IPT, neutralization test – used for detection of virus in fresh tissues and feaces
|
Last modified: Monday, 19 March 2012, 8:38 AM