Systematic Veterinary Bacteriology and Mycology

HISTORY

• Clostridial enterotoxaemias are acute, highly fatal intoxications that affect sheep, lambs, calves, piglets and occasionally foals.
• The diseases are caused by the major exotoxins (enterotoxins) of Clostridium perfringens types B, C, D and occasionally types A and E.
• The bacillus was originally cultivated by Achalme (1891), but it was first described in detail by Welch and Nuttal (1892)-who isolated it from the blood and organs of cadaver.