Bio Chemistry

BIOCHEMISTRY 3(2+1)

Lesson 17 : Glycolysis

Fate of pyruvate

Under anaerobic conditions, cells must be able to regenerate NAD+ or glycolysis will stop.

Usually regenerated by oxidative phosphorylation, but that requires O2.

There are 2 anaerobic pathways that use NADH and regenerate NAD+.

1. Alcoholic fermentation- Conversion of pyruvate to ethanol




2. lactate fermentation
   
   



Lactate causes muscles to ache. Also produced by bacterial fermentation of lactose.

3. Entry into citric acid cycle