Unit 15 - Adjuvants15.1. Introduction
Adjuvants can act as immunostimulators, immunomodulators and immunopotentiators. They can either be administered in combination with or before or after the immunization while some of them can also be given alone. Those are given along with the antigen are FCA, FIA, MDP, polynucleotides, aluminium salts, endotoxins etc. Some of them are immunostimulants and given after the antigen administration, they include glucan and others, however, if given before, they cause immune tolerance. Some are given as immunopotentiators to restore the depressed immunity and others are either given alone or prior to antigenic stimulation. These include levamisole, BCG, dextran sulphate, etc.
Last modified: Friday, 22 June 2012, 9:51 AM