Neuromuscular, Digestive and Respiratory Systems: Metabolic alkalosis

Metabolic alkalosis

METABOLIC ALKALOSIS

Metabolic alkalosis, (vomiting, K⁺ deficiency) involves the gain of base (OH^- or HCO₃^-) or loss of strong acid by ECF. In these conditions, there is an increase in HCO₃ in ECF, resulting in increased base content.
The response of the body is opposite to the one observed in metabolic acidosis.
Alkalemia results in rise in pH which will depress pulmonary ventilation and PCO₂ will rise. This respiratory compensation thus will bring pH back to normal.
Renal correction consists of decreased secretion of pH ions and so increased excretion of HCO₂.

Last modified: Saturday, 4 June 2011, 7:49 AM

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VPB 121: Veterinary Physiology - II (2+1)

Metabolic alkalosis

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