AGB 121: Principles of Animal Genetics and Population Genetics (2+1)

CHARACTERISTICS OF SEX-LINKED INHERITANCE

Features of sex-linked recessive diseases

• The frequency is higher in heterogametic than homogametic sex.
• It is transmitted from affected man through normal daughter to half of the grandsons.
• Does not occur in a woman unless her father has it.
• All the sons of the woman having this trait are affected.

Features of sex-linked dominant diseases

• More common in females.
• All female offspring of affected male will be affected
• If mother is normal sons will not be affected with the diseases.