AGB 121: Principles of Animal Genetics and Population Genetics (2+1)

CHROMOSOME MAPPING

• "Gene mapping" refers to the mapping of genes to specific locations on chromosomes.
• There are two types of gene mapping:
1. Genetic / Linkage Mapping - using linkage analysis to determine the relative position between two genes on a chromosome.
2. Physical / Cytological Mapping - using all available molecular biology techniques to examine DNA molecules directly to determine the absolute position of a gene on a chromosome.
• The first chromosome maps were made in 1913 by A.H. Sturtevant.
• Drosophila is the earliest material used by the scientists, for constructing maps.