VPT 321: Veterinary Neuropharmacology (2+1)

ROTO ROD TEST 

• Mice are placed on the horizontal rotating wooden rod / iron ros with serrations having a diameter 30 mm and rotating at the rate of 5 rotations per minute.
• Circular sections divide the linear space of the rod into 10 lengths, so that 10 mice are tested together.
• The control mouse is able to remain on the rod for 3 or more minutes in two successive trials are selected and placed in groups of five.
• Each group is injected with a drug and placed on the rod at intervals of 30, 60, 90,120 and 150 minutes after dosage.
• If the animals fails more than once to remain on the rod for 3 minutes, the test is considered positive, which is motor incordination is present.