Introductory Microbiology

Synchronous culture

• A system that closely resembles and amplifies the behaviour of single cells is synchronous culture which contain cells that are physiologically identical and are in the same stage of division cycle. A synchronous population can be generated either by physically separating cells in the same stage of division or by forcing a cell population to attain an identical physiological condition by a change in the environment.
• Several methods are available to get synchronous cultures are by centrifugation, filtration or by periodic changes in nutritional and environmental conditions. In a synchronous culture since the cells are physiologically identical, cell division occurs periodically at constant intervals.