Glycosides

GLYCOSIDES

Digitalis purpurea (foxglove plant)

  • Glycosides are non-nitrogenous substances obtained from plants.
  • The glycosides on hydrolysis yield two molecules namely a sugar molecule and a ‘genine’ or ‘aglycone’ molecule.
  • Sugar helps in the dissolution of the preparation while the pharmacological action rests with the ‘aglycone’.
  • When the sugar molecule is glucose, the glycoside is known as glucoside.
  • Cardiac glycosides digitalis, strophanthus and squill play a major role in the treatment of congestive cardiac failure.
  • Cyanogenetic glycoside is one in which hydrocyanic acid is released on glycolysis.
Last modified: Wednesday, 25 April 2012, 5:20 AM