Henderson and Hasselbalch equation

HENDERSON AND HASSELBALCH EQUATION

  • Henderson Hasselbalch equation is used to calculate the percent of a drug that exists in ionized form or to determine the concentration of a drug across the biologic membrane.

Henderson-Hasselbalch equation

  • Given this formula, if a drug is having a pKa of 4.4, and given the pH of plasma and gastric mucosa are 7.4 and 4.4 respectively, then

HH equation

Last modified: Sunday, 11 December 2011, 10:36 AM