Classification of antihypertensive drugs
These are agents used to reduce the elvate blood pressure. They can be classified based on the mechanism of action as under:
- Agents interfering with sympathetic activity
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Alpha adrenergic receptor blockers: Phentolamine, tolazoline, prazosin,
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Beta adrenergic bolckers: Propranolol, Atenolol, Metoprolol
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Alpha and Beta adrenergic blocker: Labetalol
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Agents interfering with sentral sympathetic activity: Clonidine
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Vasodilators
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Nitrates: Amyl nitrate, isosorbide dinitrate, glyceryl trinitrate ( nitroglycerine) are used as vasodilators.
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Calcium channel blockers: Drugs under this category include verapamil, diltiazem, nifedipine, nimodipine and amlodipine.
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Potassium channel activators: Drugs under this category include cromokalin, pinacidil, minoridil and diazoxide.
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Agents that act by increasing cyclic nucleotide concentration: Nitroprusside
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Vasodilators with unknown mechanism of action: Hydralazine
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Agents acting through inhibition of Angiotensin
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Last modified: Wednesday, 25 April 2012, 11:44 AM