Etiology and epidemiology of nutritional haemoglobinuria

ETIOLOGY AND EPIDEMIOLOGY NUTRITIONAL HAEMOGLOBINURIA

Etiology

  • Ration low in P, hay and grass from low P area, draught
  • Cu deficiency (incidence reduced when supplemented)

Precipitating factor

  • Grazing Brassica sp. plants, rape and turnip and other cruciferous plants, large quantity of beet pulp, sugar cane top (low in p).
  • Exposure to cold weather, cold water - erythrocytes becomes more sensitive to hemolysis when there is hypophosphatemia & hypocupremia

Epidemiology

  • Prolonged hypophosphatemia is an important predisposing factor
  • 'P' deficient soil and drought condition act as precipitating factors
  • 50% mortality and 40% morbidity
  • Adult cow & she buffalo 3-6 weeks after delivery are more prone.
  • Animals in 3-6th Lactation are more prone
  • Geographical distribution: Throughout the world including India
  • In India: It is very common in North India – Punjab, Haryana, M.P, Rajasthan, Western part of Maharashtra.
  • In Europe & North America the diseases is more common during prolonged period of housing.
Last modified: Friday, 20 January 2012, 6:41 AM