Veterinary Taxicology

CLASSIFICATION OF FACTORS

• The factors modifying the action of a poison include

  • toxicant-related factors like
    • chemical identity
    • physical characteristics
    • vehicle
    • formulation
  • exposure-related factors like
    • dose
    • route and site of administration
    • frequency and duration of exposure
    • time of exposure
  • subject-related factors like
    • species
    • strain or breed
    • individual differences
    • age
    • nutritional status
    • sex
    • pregnancy
    • diseases
  • environmental factors like
    • temperature
    • stress
    • ventilation