Veterinary Preventive Medicine-II

CLINICAL SIGNS

• Incubation period of the disease ranges from 2-8 weeks. As a whole the following four clinical findings have been outlined but it is not a rigid one and all the manifestations may follow in a case.

S.No.	Form of the disease	General clinical signs
1	Peracute form	High rise of temperature, dyspnoea and diarrhoea but with out any head and eye lesions
2	Head and eye form	Clinical course of around 9 days characterized by nervous syndrome like paralysis and convulsion prior to death
3	Intestinal form
4	Inapparent (mild) form

• The disease as a whole is characterized by
  • Dullness, depression, anorexia and high rise of temperature ranging from 105-108ºF. This is followed by ocular and nasal discharge.
  • Discharges are initially mucoid in nature which soon become mucoprulent, stingy and contain blood flecks. There is acceleration of pulse and respiratory rate. Signs of dysponea may be evident.
  • There is oedema of the eyelids leading to panopthalmitis
  • Changes in the epithelium of mouth cavity comprising of congestive changes, precisely on the gum, beneath the tongue, hard palate and oral papillae. Erosive and ultimate necrotic changes may follow in the oral mucosa giving rise to offensive odour from the mouth.
  • Ocular lesions– Photophobia and meiosis, corneal opacity, blindness
  • Cutaneous lesions (congestion, petechiation, bluish discolouration and thickening) localized or generalized. prominent on the muzzle, skin of the hoof, scrotum, base of the horn and teat.

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