Systematic Veterinary Virology

GENERAL CHARACTERS

• Definition: Infectious canine hepatitis (ICH) is a contagious disease of dogs with signs that vary from a slight fever and congestion of the mucous membranes to severe depression, marked leukopenia, and prolonged bleeding time
• Classification

Baltimore group	Group I ds DNA viruses
Family	Adenoviridae
Genus	Mastadenovirus
Species	Canine adenovirus 1 (CAV 1)

• Synonyms: Rubarth’s disease
• Morphology: As specified above
• OIE Listing: Not listed by OIE
• Risk group: No risk to human beings
• Referral laboratory: Not provided by OIE
• Replication: As provided above
• Resistance: CAV-1 is resistant to lipid solvents and survives outside the host for long durations extending to many months. The virus is sensitive to 1-3% solution of sodium hypochlorite (Bleaching powder).
• HA property: The virus has no HA property
• Strains and serotypes: CAV 1 is antigenically related to CAV 2, which causes infectious tracheobronchitis in dogs