Veterinary Physiology-III

BY METABOLITE CONCENTRATION

• It is one of the simplest controls of hormone secretion e.g. a rising level of blood glucose signals release of blood sugar lowering hormone, insulin.
• Insulin facilitates glucose movement through the cell membrane, which is either metabolised or stored in the form of glycogen in the liver for later use. When the blood glucose level drops below normal, the blood glucose raising hormone, glucagon is released from the alpha cells of the pancreatic islets.
• It stimulates glycogenolysis of the glycogen stores of the liver, thereby raising the glucose level back to normal.