Pancreatic polypeptide

PANCREATIC POLYPEPTIDE

  • Pancreatic polypeptide is a peptide hormone, containing 36 amino acids and secreted by the stimulation of F (PP) cells in the islets of pancreas.
  • It is related to two other 36 amino acid polypeptides – polypeptide YY (PYY) of intestine and neuropeptide Y (NPY)of brain and ANS.
  • It increases gut motility and gastric emptying, stimu­lates the secretions of the intestinal hormones- gastrin, secretin and CCK.
  • It inhibits pancreatic enzyme secretion and gall bladder contraction.
  • Protein has stimulatory effect on its secretion, somatostatin inhibits its release.
Last modified: Thursday, 9 February 2012, 10:48 AM