Pathogenesis

PATHOGENESIS OF DIABETES MELLITUS (DM) 

  • Autoimmune destruction of pancreatic β cells may be the cause of type 1 DM (formerly called insulin-dependent DM).
  • The etiology of type 2 DM is less clear, and is characterized by an inadequate secretion and an altered action of insulin.
  • Type 3 DM, also called secondary DM, results from other diseases, hormonal influences or medications causing a decrease of insulin secretion or an altered action of insulin (pancreatic neoplasia, pancreatitis, cortisol, growth hormone, etc ...).
  • Transient DM:  Resolution of DM seems to be closely related to a rigorous control of blood glucose and can be definitive or transitional and last a period of months or yearS
Last modified: Tuesday, 8 March 2011, 11:57 PM