Autoimmune hemolytic anemia
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AUTOIMMUNE HEMOLYTIC ANAEMIA
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General
- Primary or secondary
- Species differences
- Different classes
- warm antibody type
- warm agglutinins
- in vivo hemolysis
- incomplete antibody type
- cold antibody type
- cold agglutinins
- nonagglutinating hemolytic cold antibody type
Etiology
Clinical signs
Variable depending upon the antibody type
- Anemia
- Tachypnea
- Tachycardia
- Icterus
- Hemoglobinuria
- Lethargy
- Spleenomegaly
- Hepatomegaly
- Lymphadenopathy
- Acrocyanosis
Diagnosis
- Hematological findings
- Biochemistry findings
- Immunological findings
- Bone marrow biopsy
- History and physical exam
- Urinalysis
- Radiographic findings
- Therapy
- High dose steroids initial
- Blood transfusion
- Cytotoxic drugs
- Splenectomy
- Treat the offending parasite, drug reaction, infection
- Prognosis is poor to guarded
- Plasmapheresis
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Last modified: Tuesday, 5 June 2012, 1:06 PM