Veterinary Clinical Medicine-I (General and Systemic)

PATHOPHYSIOLOGY

• Bacteria usually gain access to the prostate gland by ascending the urethra and overcoming the lower urinary tract host defense mechanisms.
• Incomplete resolution of acute bacterial prostatitis can lead to chronic bacterial prostatitis or abscess formation;
• Intraprostatic accumulation of prostatic secretions (e.g., in animals with cystic benign prostatic hyperplasia or squamous metaplasia)  become secondarily infected, resulting in chronic bacterial prostatitis or prostatic abscess.