Medicine Section

NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

How to act, when ingested?

• Ingested when owner administ or self-ingestion with canine formulations.
• Cats have a low tolerance for NSAIDs.
• Gastrointestinal - vomiting, diarrhea, ulceration, hemorrhage, and ulcer perforation.
• Higher doses cause acute renal failure.
• CNS signs - seizures and comas at high doses.
• The more common drugs that can cause this syndrome include carprofen, ibuprofen, deracoxib, naproxen, etodolac, meloxicam, and indomethacin.
• If ingsted 4 hours before nad there is vomiting signs induce vomiting and activated charcoal.
• H2blocker (e.g. ranitidine or famotidine) or proton-pump inhibitor (e.g. omeprazole), as well as sucralfate and misoprostol (1 to 3 µg/kg orally b.i.d.) for seven to 10 days.
• Fluid therapy at twice the maintenance rate for at least 48 hours to prevent renal damage.