Fish Immunology (1+1)

Unit 10 - Immunological Memory

10.3. Response
B and T cells that are stimulated by antigen divide, during division B cell receptor sometimes mutates leading to increase in the affinity of its daughter cells for the antigen. This B cells change into plasma cells and secrete antibodies which eliminate the antigen. Once the antigen is cleared the B cells with increased affinity for the antigen are selected for keeping memory for an antigen.