VPB 112: General Veterinary Biochemistry (1+1)

LYSOPHOSPHOLIPIDS

• They are intermediates in the metabolism of phosphoglycerols. E.g., lysolecithine. It does not contain fatty acid at 2nd position.
• Snake venom contains an enzyme called phospholipase A2, which releases fatty acid from the C2 position producing lysolecithine.
• It acts as a detergent and is responsible for lysis of cell membrane particularly in erythrocytes causing hemolysis.