Regulation of Calcium Metabolism

REGULATION OF CALCIUM METABOLISM

  • Whenever blood calcium level decreases below the normal, parathyroid gland is stimulated to secrete parathormone. This hormone mobilizes calcium from the bone and also facilitates reabsorption of calcium in the kidney.
  • It also increases calcium absorption in the small intestine by increasing the synthesis of 1,25 dihydroxy cholecalciferol (active form of vitamin D) from 25 hydroxy cholecalciferol in the kidneys, which in turn increases the synthesis of calcium binding protein resulting in increased calcium absorption.
  • High level of blood calcium stimulates the secretion of calcitonin, which has antagonistic action to that of parathormone.
Last modified: Saturday, 27 August 2011, 7:26 AM