VPB 121: Veterinary Physiology - II (2+1)

EXCITATION CONTRACTION COUPLING

• The arrival of an Action Potential at Sarcoplasmic Reticulum causes release of Ca²⁺ down the concentration gradient to sarcoplasmic reticulum.Released Ca²⁺ causes conformational changes to effect contraction. As action potential passes,Ca²are pumped again to sarcoplasmic reticulum and relaxation happens. This cycle is known as Excitation Contraction Coupling.