VPB 121: Veterinary Physiology - II (2+1)

MUSCLE PATHOLOGIES

• Skeletal muscle pathologies are classified into 3 categories
• Muscle atrophies that have a neural involvement that derive form disease of ventral root cells, motor nerve roots or peripheral nerves
• Disorders of neuro muscular transmission including myasthenia gravis, poisoning and various acetyl cholinesterase compounds botulism and tick paralysis
• Disorder of muscle cell itself which are genetically determined myopatheis, muscle damage by external agents including physical damage, toxins and drugs such as steroids with chloroquine, inflammatory reactions due to viral or bacterial or parasite infestations and autoimmune disease (polymyositis), muscle disorders associated with endocrine or metabolic disease, myopathies associated with malignant disease such as rhabadomyeloma, tumors, amyloidosis and paroxysmal myoglobinuria.