VPB 121: Veterinary Physiology - II (2+1)

GASTRIC GLANDS

• The glandular mucosa of the stomach has many pores known as gastric pits.

• The surface area of the stomach lining the pits is covered with mucous cells which secrete mucus to protect the surface epithelium.
• Secretions of gastric glands
  • Cardiac glands secrete only mucus
  • Parietal/fundic glands secrete HCl and pepsinogen
  • Pyloric glands secrete mucus and gastrin.
• Cell types of fundic glands
  • Fundic gland contain three main types of cells.
    • Body chief cells or peptic cells are locate at the base of the gland secrete proteolytic enzymes (Pepsin and Rennin)
    • Parietal or oxyntic cells are present at the upper third of the gland is the site of HCl secretion.
    • Neck chief cells, placed near the surface epithelium near the upper part of the gland secret mucus and a mucoprotein “Intrinsic factor" required for Vit.B₁₂ absorption from the intestine is necessary for erythropoiesis. 

Cells of pyloric glands

• The pyloric glands are structurally similar to the parietal glands
• Has body chief cells and neck chief cells only.
• Parietal cells are absent.
• “G” cells secrets Gastrin (Gut hormone).