Regulation of pancreatic secretion

REGULATION OF PANCREATIC SECRETION

Nervous regulation

  • In three phases
    • Cephalic phase.
    • Gastric phase. 
    • Intestinal phase.  

  • Cephalic phase:  The cephalic phase of gastric secretions , simultaneously transmit the impulses  along the vagi to pancreas; results in pancreatic secretion  rich in enzymes, but little water and electrolytes.
  • Gastric phase: Distension of stomach due to entry of food into the stomach casuse   reflex stimulation of pancreatic secretion through vagovagal reflex. 
  • Intestinal phase: Distension of intestine following the entery of food into the small intestine, stimulates the  production of pancreatic enzymes and their secretion. This phase is controlled by both  intrinsic nerves of the intensine and vagus. Acetylcholine released by the vagal action and local nerve reflexes sensitise the pancreas for the action of  secretin and CCK.
Last modified: Thursday, 9 June 2011, 5:36 AM