VIiral Haemagglutination

VIRAL HAEMAGGLUTINATION
  • Some viruses bind to red blood cells of certain animal species and cause agglutination. Binding occurs by interaction of viral protein located on the capsid or envelope with receptors on RBC.
  • Agglutination is result of bridging effect of one virion binding to two RBCs simultaneously and these inturn bound to other RBCs by additional virions. This causes a lattice-like aggregate of RBCs.
  • Haemagglutination is influenced by pH and temperature. Haemagglutination is useful in concentration and purification of some viruses and to detect virus in suspected materials.
Last modified: Sunday, 4 December 2011, 6:24 AM