Adjuvants

ADJUVANTS

  • Adjuvants provide depots effect to an antigen at the site of administration which allows persistence and slow release of antigen over an extended period of time resulting in higher and prolonged immune response.
  • Adjuvants increase immunogenicity of weak antigens.
  • It helps in stimulation of cell-mediated immune response.
  • Addition of adjuvant reduces the cost and dose of an antigen.
  • Examples, mineral oils (Aluminium hydroxide, Liquid paraffin etc.) Vegetable oils (Ground Nut oil, Montanide etc.), Mycobacterial products (Freund’s adjuvant) etc.
  • Some other delivery systems are ISCOM (Immunostimulating complex), Nanoparticles etc.
Last modified: Thursday, 26 August 2010, 10:28 AM