Pathogenesis

PATHOGENESIS

  • The incubation period ranges from several weeks to six months.
  • Following the initial invasion of the skin, the organism spreads through the lymphatic vessels to the regional lymph nodes, and in more advanced cases involves the internal organs.
  • Nodular and chronic suppurating lesions are evident in the skin overlying lymph vessels and nodes.
  • When mucosal lesions occur, most are confined to the upper respiratory tract and eyes.
  • The nasal infection is usually accompanied by mucopurulent discharge containing large numbers of the fungus.
Last modified: Monday, 4 June 2012, 6:38 AM