Adverse effects

ADVERSE EFFECTS

  • CNS : drowsiness, lethargy, mental confusion
  • Alpha adrenergic blockade - hypotension, inhibition of ejaculation
  • Anticholinergic: Dry mouth, constipation, urinary hesitancy
  • Endocrinal: Glactorrhoea, gynaecomastia, infertility.
  •  Extrapyramidal effects: Rigidity, tremor, shuffling gait
  • Acute muscular dystonia - muscle spasms, torticollis, locked jaw.
  • Akathesia - restlessness, feeling of discomfort, apparent agitation
  • Tardive dyskinesia -purposeless involuntary facial and limb movements, constant chewing, pouting , puffing of cheeks, lip licking.
  • Blue pigmentation of exposed skin, corneal opacity, retinal degeneration.
  • Hypersensitivity reactions - rashes, urticaria, contact dermatitis, photosensitivity and agranulocytosis.
Last modified: Sunday, 2 October 2011, 4:51 PM