VPT 421: Veterinary Toxicology (2+0)

TREATMENT

• In cases of recent ingestion of preformed botulinus toxin, measures to remove the contents of the gastrointestinal tract as well as activated charcoal and a cathartic are indicated.
• Sodium/potassium penicillin intravenously to eliminate proliferating C. botulinum organisms.
• Supportive care including padding, provision of a warm, dry environment and turning the animal with assistance in eating, drinking, urination and defecation are indicated. Supportive alimentation is required in a large number of cases. Prolonged ventilation for respiratory paralysis is probably not going to be practical for any animal patient.
• In cattle, carbamylcholine to stimulate gastrointestinal motility and enhance removal of the toxin seemed to enhance the probability of survival in a small number of animals.