Introduction

Introduction

    • The synthesis of every protein molecule in a cell is directed by intracellular DNA.
    • There are two aspects to understand how this is accomplished – Information aspect and Chemical aspect.
    • Information aspect meant the mechanism by which a base sequence in a DNA molecule is translated into an amino acid sequence of a polypeptide chain.
    • The chemical aspect refers to the actual process of synthesis of the protein: the means of initiating synthesis; linking together the amino acids in the correct order; terminating the chain; releasing the finished chain from the synthetic apparatus; folding the chain, and often postsynthetic modification of the newly synthesized chain.
    • The overall process is called as Translation. Protein synthesis can be divided into three stages:
      1. Polypeptide chain initiation,
      2. Chain elongation and
      3. Chain termination.

Last modified: Wednesday, 28 March 2012, 11:26 PM