Introduction
- The synthesis of every protein molecule in a cell is directed by intracellular DNA.
- There are two aspects to understand how this is accomplished – Information aspect and Chemical aspect.
- Information aspect meant the mechanism by which a base sequence in a DNA molecule is translated into an amino acid sequence of a polypeptide chain.
- The chemical aspect refers to the actual process of synthesis of the protein: the means of initiating synthesis; linking together the amino acids in the correct order; terminating the chain; releasing the finished chain from the synthetic apparatus; folding the chain, and often postsynthetic modification of the newly synthesized chain.
- The overall process is called as Translation. Protein synthesis can be divided into three stages:
- Polypeptide chain initiation,
- Chain elongation and
- Chain termination.
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Last modified: Wednesday, 28 March 2012, 11:26 PM