VITAMIN D
Vitamin D is otherwise known as ‘sunshine vitamin’ as it can be synthesized from sunlight by our body.
Functions
- Vitamin D promotes the absorption of calcium and phosphorus from the small intestine
- In the DNA vitamin D helps to form active calcium binding protein
- It also maintains the concentration of calcium and phosphorus in the blood
- Vitamin D helps the deposition of calcium phosphate in the bone. In rachitic children there may be delay in dentition and malformation of the teeth occurs
Deficiency
- Deficiency of vitamin D results in poor absorption of calcium and phosphorus from the intestine and excessive loss of them in the urine and faeces.
- Concentration of calcium in the plasma is diminished and it produces tetany which is characterized by hyperexcitability of the nervous system.
- This stimulates the parathyroid glands to decalcify bone calcium to raise the plasma calcium level.
- Deficiency of vitamin D leads to rickets in children and osteomalacia in adults
Rickets
- The name of Rickets is given to vitamin D deficiency after a famous English bone setter by EII. In mild deficiency of vitamin D, the symptoms shown are restlessness and irritability.
- Rickets is a disease of infancy and childhood. Calcium and phosphorus are not deposited enough to form strong bones and as a result the leg bones become bent and deformed.
Symptoms
- Small round unossified areas are developed near skull bones
- Projections are formed on the osteochondal junction of the ribs.
- It resembles a rosary and it is known as ‘rickets rosary’.
- The abdomen is distended and chest deformities like depression of ribs attached to diaphragm take place. This is known as Harrison’s sulcus and gives an appearance of ‘pigeon breast’.
- In a later stage, pelvic deformities, bow legs and/or knock knees develop.
- Nutritional rickets occur in infants and children of poor families. Premature infants are more susceptible to rickets
Osteomalacia
- Osteomalacia occurs among adults.
- It is often known as ‘adult rickets’. Osteomalacia is most common among women who live on a poor diet lacking in calcium and vitamin D. Pregnant women are more prone to this.
- It is mainly because of the increase in weight during pregnancy accompanied by the deficiency of vitamin D.
- It is again common among women who observe ‘purdah’.
- Repeated pregnancies and prolonged lactation further deplete calcium stores which results in osteomalacia.
- Pain, softening and tenderness in the bones and fractures are the common complaints of the patients of osteomalacia.
Sources
- Best sources: Fish liver oils, egg yolk, milk, butter, ghee and fortified foods
- Best natural source: Sun light
Requirements
- The daily requirements of vitamin D for infants, children, pregnant and nursing women have been estimates to be 400 IU (10µg) and for older children and adults about 200 IU (5µg).
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Last modified: Tuesday, 5 June 2012, 5:47 AM