Intravenous route
Parenteral administration
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While considering parenteral administration, the points of importance include
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Volume to be administered
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Concentration of the drug
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pH
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Toxicity
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Viscosity
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Particle size, if suspension is used
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Adjuvant used in the preparation
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In general, parenteral administration requires skill of injection and use of sterile equipment. Parenteral preparations are normally used as solutions or suspensions.
Intravenous administration
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Advantages
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Extremely rapid onset of action
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Drug levels can be controlled more accurately
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Suitable for irritant drugs
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Suitable for large volumes of drugs
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Disadvantages
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Most dangerous route as toxicity can easily occur
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Drugs must be in aqueous solution
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Must be performed slowly
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Once injected, drug cannot be retrieved
Sites for venipuncture in different species
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Cattle, sheep and goat - At any point along the whole length of the jugular vein in the jugular furrow, on the venterolateral aspect of the neck on either side
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Horse - External jugular vein in the jugular furrow only in the cranial part of the neck.
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Pig - Auricular vein
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Dog - saphenous vein on the medial aspect of the leg or recurrent tarsal vein on the dorsal aspect of the leg.
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Last modified: Wednesday, 25 April 2012, 5:31 AM