Special Veterinary Pathology

MICROSCOPIC LESIONS

 Actinomycosis

• Note the granulomatous lesion with characteristic actinobody with giant cells and macrophages with gram positive rods in the centre (Clubs) 

Actinobacillosis – Tongue

• Note the granulomatous lesion with central colony of gram negative organisms arranged as ‘’Indian club’’ surrounded by neutrophils, macrophages, epithelioid cells and giant cells. Around this layer may be found lymphocytes, plasma cells and eosinophils and beyond a non-specific vascular fibrous tissue.

Tuberculosis – Lung

• Note the granulomatous nature of lesion
  • Note the loss of structural details of the tissue at the lesion. Note the central area of calcification/caeseation necrois. Note the Langhan’s type giant cells at the periphery of lesion with a zone of endothelioid cells and lymphocytes
• TB acid fast bacilli

TB acid fast bacilli

 

Johne’s disease-Intestine

• Chronic granulomatous enteritis- Note the large number of epitheloid cells and plasma cells especially in the lamina propria and the submucosa, atrophy of the intestinal glands and distortion of villi

Chronic granulomatous enteritis
Note the large number of epitheloid cells and plasma cells especially
in the lamina propria and the submucosa, atrophy of the
intestinal glands and distortion of villi

• JD Acid fast bacilli 

JD acid fast bacilli

Black quarter – Skeletal muscle

• Note the disruption and necrosis of muscle fibres and edematous fluid dissecting the muscle fibres

BQ-Note the disruption and necrosis of muscle fibres
with infiltration of neutrophils

Glanders – Lung

• Note the central zone of degenerated leucocytes and alveolar cells surrounded by a vascular zone

Leptospirosis – Kidney – Dog

• Note the interstitial space containing edematous fluid and infiltrated by lymphocytes and plasma cells. The tubular epithelium shows degenerative changes

Interstitial nephritis

Anthrax- Bacilli

Rod shaped capsulated organism

Pasteurellosis- Bipolars

Pasteurellosis - Bipolars

Contagious bovine pleuropneumonia - Lung

• Marbling and thickened intera lveolar septa

Marbling and thickened intera lveolar septa	TB-Note the central area of calcification/caeseation necrois. Note the Langhan’s type giant cells at the periphery of lesion with a zone of endothelioid cells and lymphocytes