Veterinary Immunology and Serology

MOLECULAR SIZE

• Foreign proteins are some of the best antigen.
• In general, the larger the molecular weight, the better are their antigenic properties.
• For example, ovalbumin (mol. wt. 40,000 Da). But there are some exceptions e.g. natural protein glucagon (2600 Da) is a good antigen.
• Penicillin and aspirin are not good antigen since their molecular weight is less than 1000 dalton.