Veterinary Immunology and Serology

DOSAGE AND ROUTE OF ADMINISTRATION

• An insufficient dose will not evoke an immune response either because it fails to activate enough lymphocytes or because it induces a non-responsive state.
• An excessively high dose also can fail to induce a response because it causes lymphocytes to enter a non responsive state.
• For inducing strong immune response, repeated administrations (boosters) are required.
• Antigens are generally administered parenterally i.e. by routes other than the digestive tract.