Veterinary Immunology and Serology

Types based on T cell response

ANTIGENIC TYPES BASED ON T CELL RESPONSE

T dependent antigen

• Complex antigens such as RBC, serum proteins etc. They are rapidly metabolized, require T cell help and produce memory and class switching.

T independent antigen

• LPS of E coli, pneumococcal polysaccharide, flagellin , Lectin, Con A PHA, Pokeweed mitogen etc., composed of repeating units. They are slowly metabolized, no memory or class switching.