Hepato renal syndrome indicates combined liver and kidney failure which occurs after severe hemorrhage, diarrhea, surgery or removal of fluid from abdomen.
Nitrogenous products of metabolism accumulate as urine output decreases. There is an accompanied severe disturbance in electrolytes. Kidney function has to be restored immediately to prevent death. Levels of Nitric Oxide (NO) is considered to be responsible for kidney failure.
Correction of serum electrolyte levels should be given priority and at the first sign of any mental change, usage of diuretics should be discontinued. Restriction of fluid will also prevent cerebral edema.
Proteins are restricted and nasogastric feeding is resorted to. Intestinal flora are reduced by giving enemas and washes and by administering antibiotics. If required, blood transfusion may also be given.
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