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10.1.8 Pantothenic Acid
Pantothenic acid is formed by combination of pantoic acid and ß-alanine. Coenzyme A (CoA) is the coenzyme of pantothenic acid. It also forms a component of the acyl carrier protein (ACP).
Functions: The thiol group acts as a carrier of acyl radicals in both CoA and ACP. This occurs with CoA in reactions of the citric acid cycle, fatty acid synthesis and oxidation, acetylation reactions, and cholesterol synthesis. ACP participates in reactions concerned with fatty acid synthesis. It is customary to abbreviate the structure of the free (ie, reduced) CoA as CoA-SH, in which the reactive SH group of the coenzymes is designated.
Deficiency: Deficiency of pantothenic acid is rare. This is because the substance is widely distributed in foods.
RDA
Infants :1-2mg Children :4-5mg Adult (males& female) :5-10mg Pregnant& Lactating women :10-15mg
Sources Richest Sources : Liver, kidney Good sources : Milk, meat, eggs and leafy vegetables Fair sources : Fruits and vegetables. |