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6.1.5.6 Fluroscence in situ hybridization (FISH)
The radiolabelled DNA probe for in situ hybridization has been replaced by flurocent dye-labelled DNA probe in the recent past. The flurocence signal is detected by the flurocent microscope and various colour patterns on chromosome can be obtained. This technique is now used for homologous chromosome identification and studying the location of a DNA sequence on the chromosome. In the near future greater use of this technique would be found in fish cytotaxonomy and genetic studies. |
Last modified: Monday, 23 January 2012, 11:44 AM