Pathogenesis

PATHOGENESIS OF BACILLUS
  • Anthrax can occur in virtually all mammalian species but birds are highly resistant.
  • The main routes of entry of endospores are by ingestion, from soil when grazing or in contaminated food, and by infection of wounds.
  • Inhalation of spores occurs in man, but to a lesser extent in animals.
  • Transmission by biting insects may be important, especially during an outbreak of anthrax.
  • Cattle, sheep and goats are most susceptible to infection, while horses and humans occupy an intermediate position and pigs and carnivores are comparatively resistant, but can succumb if the infective dose is high.
Last modified: Monday, 4 June 2012, 4:20 AM