VMC 311: Systematic Veterinary Bacteriology and Mycology (2+1)

BLASTOMYCOSIS

• Etiologic agent: Blastomyces dermatitidis
• Source: soil enriched with decaying organic materils
• Epidemiology: Primarily North America with sporadic cases reported from India, Africa and the Middle East.
• Clinical Signs
  • Cutaneous lesions (Pustules, verrucous or ulcerated lesions) or subcutaneous abscesses.
  • Acute pulmonary disease with cough, pleuritic pain, chills, and low-grade fever.
  • Chronic pulmonary disease with productive cough, fever, weight loss, dyspnoea, and fatigue.
  • Dissemination to skin, bone and genitourinary tract may also occur.
• Lesions: Tissue responses suppurative and granulamatous
• Treatment: Amphotericin B or Ketoconazole