VPB 321: Animal Biotechnology (2+1)

METHODS OF GENOME SEQUENCING

• BAC-to-BAC method, the first to be employed in human genome studies, is slow but sure. The BAC-to-BAC approach, also referred to as the map-based method.
• Whole genome shotgun sequencing, brings speed into the picture, enabling researchers to do the job in months to a year. The shotgun method was developed by J. Craig Venter in 1996 when he was at the Institute for Genomic Research (TIGR).